Restylane® Defyne


    Crafted with XpresHAn Technology™, Restylane® Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines). Using innovative cross-linking technology, Restylane® Defyne is a hyaluronic acid dermal filler that is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions. Now the first and only FDA-approved chin filler!

    What is Restylane® Defyne?

    Restylane® Defyne contains hyaluronic acid, a naturally occurring sugar found in the body that provides moisture, volume, and elasticity for the skin. The dermal filler also contains a small amount of lidocaine, a local anesthetic commonly used to numb the skin and minimize discomfort during the procedure.

    The hyaluronic acid is crosslinked with BDDE, an ingredient that helps form a network of hyaluronic acid to provide a smooth gel texture that lasts longer and appears more natural.

    Benefits of Restylane® Defyne

    As we age, the facial skin begins to lose elasticity and volume, leading to more visible “laugh lines” that run from the sides of the nose toward the corners of the mouth. Restylane® Defyne is designed to temporarily smooth out these wrinkles and folds and restore a natural, soft look to the face.

    Restylane® Defyne may also be used to augment the chin region to create a more refined chin profile in patients with mild to moderate chin retrusion. The procedure may improve the profile, shape, and size of the chin, with results lasting up to 12 months.


    Before the Treatment Session

    Before scheduling treatment, patients should share details about their medical history with their medical professional to determine if they are an appropriate candidate for treatment. During the initial consultation, the doctor will ask questions about possible allergies to ensure patients won’t experience serious allergic reactions to Restylane® Defyne. Patients should tell their doctor if they:

    • Have severe allergies with a history of severe reactions (anaphylaxis)
    • Are allergic to the anesthetic lidocaine or the proteins used to make the hyaluronic acid in Restylane® Defyne
    • Have a history of scarring
    • Are pregnant, breastfeeding, or planning to become pregnant soon
    • Intend to undergo laser treatment or chemical peels in the near future

    What to Expect

    Before making the injections, the medical professional will cleanse the treatment area and apply a topical anesthetic. He or she will then make the first injection and pause to allow the anesthetic in Restylane® Defyne to further numb the treatment area. This will help to minimize discomfort during treatment.

    The doctor will make additional injections once the treatment area shows the desired results. At the end of the procedure, the doctor will gently massage the treatment area to promote even distribution and a natural appearance.

    Potential Risks and Side Effects

    After treatment, patients may experience the following temporary side effects:

    • Swelling
    • Bruising
    • Lumps/bumps formation
    • Pain/tenderness
    • Itching
    • Redness

    These side effects should resolve within one to two weeks. Other rare and serious side effects may include infection, scarring, skin discoloration, cold sores, and vision changes.

    Recovery Process

    For 24 hours after treatment, patients avoid or minimize strenuous exercise and exposure to sun or heat to reduce redness, swelling, and/or itching at the injection site. An ice pack may be applied to alleviate these side effects.

    If you’d like to smooth your laugh lines or improve the profile, shape, and size of your chin, contact the NuAge Spa today to schedule an appointment for Restylane® Defyne today!